LAB IN THE BOX
STATE OF ART REGENERATIVE TREATMENT
BACKGROUND
Regenerative therapies by using autologous stem cells is the emerging hot topic in medicine. Stem cell therapies are applied not only in aesthetics and dermatology, but also in orthopedics and in cardiovascular fields.
The obstacles related to harvesting regenerative cells, usually from bone marrow and culturing these in GMP standardized facilities, a very long process taking weeks, as well as very expensive, prevented this field from growing widely for years.
This has been dramatically changed when we learned that we can get these regenerative stem cells from fat. More accurately, adipose tissue derived stromal vascular fraction (SVF) has become a reliable and effective source, containing abundant numbers of regenerative cells. Fat tissue has 500-1000 times more regenerative cells in comparison to bone marrow in concentration.
Regarded as the golden standard in terms of cell count in SVF, enzymatic digestion of fat is still relatively expensive by nature, necessities employing expert staff, raises legal and administrative concerns, questions about altering cellular characteristics as well as time consuming (90-120 minutes), thus limiting its usage significantly. These facts have limited the usage of fat derived stem cells.
THE LIPOCUBE
Mechanical methods for SVF isolation deliver lower cell yields per cc of lipoaspirate processed in comparison to enzymatic methods. However, the composition of the cell populations in the mechanically extracted SVF are generally similar to enzymatic digestion with only slight differences. Additionally, mechanical methods have resulted to contain higher frequencies of peripheral blood cells and lower number of progenitor cells, an advantageous aspect.
The Lipocube™ is a state-of-the-art mechanical digestion device for the isolation of SVF from lipoaspirate.
ADVANTAGES OF LIPOCUBE
There is no need for a GMP facility / Your practice is basically your lab.
It is an easy to use device enabling practicians high cell yields.
The isolation time is much shorter.
There is no need for expert staff.
The manipulation of cells is minimum, a key point in legal issues.
It is a cost efficient method.
Fully enclosed system thus sterile environment.
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